I don't know if this goes for balance or whatnot, but I'd like to see frail get nerfed. If I interpret it correctly (unlikely), it's a -50 to -500% DR. I just got hit by a nightshade and ended up with a -87 DR. That seems excessive. Maybe giving it a lower limit of 0 would be enough.
You're interpreting it correctly. It's supposed to be annoying.
Only -87...I have seen -151. What I did when it was dangerous to me was to make a message / response to port out when I was hit with it and not loop in mod 9 until I could absorb the damage it can produce.